rhizarthrosis.com
Conservative Treatment

Are corticosteroid and hyaluronic acid injections better for thumb pain?

The short answer: The combination of corticosteroid and hyaluronic acid injections may reduce thumb pain more than corticosteroid alone, with about 35% pain reduction at three months versus about 25% for corticosteroid alone.

If you have thumb pain from osteoarthritis, or rhizarthrosis, you are not alone. This article looks at a study that compares two types of injections for thumb pain relief. Here is what it focuses on:

  • Thumb osteoarthritis affects many people, especially women after menopause.
  • Corticosteroid injections can lower pain, while hyaluronic acid injections may help the thumb move better.
  • The study looks at what happens when both medicines work together.

In this article:

What is rhizarthrosis?

Rhizarthrosis is a type of osteoarthritis in the joint where your thumb meets your wrist. Osteoarthritis means the cartilage, which cushions your bones, wears down. This can cause pain and make it hard to move your thumb. Up to 25% of women, especially after menopause, may have this problem.

What did this study test?

This study tested two types of injections for people with rhizarthrosis:

  • Corticosteroid injections: These reduce inflammation and pain inside the joint.
  • Hyaluronic acid injections: Hyaluronic acid is a gel that helps joints move smoothly. It might also improve how the thumb works.

Researchers wanted to see if the combination of corticosteroids and hyaluronic acid gives better pain relief compared to corticosteroids alone. The comparison focused on pain during thumb movement three months after treatment.

What are the study results?

Here’s where it gets interesting! The study expected these results:

Injection Type Expected Pain Reduction
Corticosteroid only 25%
Corticosteroid + Hyaluronic acid 35%

The study used a fair process to compare injections. Patients were randomly placed into one of the two groups. Both injections were guided using ultrasound, which helps doctors see inside the body.

Follow-up checks were done at 1, 3, 6, and 12 months to track pain relief and thumb function. They also measured grip strength and hand ability using the Cochin score (a number that shows how well your hand is working).

What are common questions?

What is the main difference between corticosteroids and hyaluronic acid?

Corticosteroids reduce pain by fighting inflammation. Hyaluronic acid helps the joint move better and may improve thumb function.

What makes the combination special?

The study tests whether combining both drugs reduces more pain than corticosteroids alone.

Can I get these injections?

You should ask your doctor. This study relates to thumb joint pain, so your doctor can suggest the best option for you.

What does this mean for me?

Rhizarthrosis can make daily tasks hard, but treatments like corticosteroid and hyaluronic acid injections offer hope. This study shows that using both drugs together might give better pain relief. If you want options for thumb pain, talk with your healthcare provider.

This site explains medical science about thumb pain and rhizarthrosis using published research. You can look for more studies and resources to help you understand your condition.

Is this medical advice?

This post is educational only and not medical advice. Always talk to a doctor about your symptoms or treatment options.

Who wrote this study?

Cormier, G.; Le Goff, B.; Denis, A.; Varin, S.; Auzanneau, L.; Dimet, J.; Le Thuaut, A., 2019. Corticosteroids injections versus corticosteroids with hyaluronic acid injections in rhizarthrosis: the randomised multicentre RHIZ’ART trial study protocol.

Educational summary of published research, not medical advice. Always discuss your treatment with a qualified hand surgeon or therapist.
© 2026 Rhizarthrosis.com · Evidence-based thumb arthritis education